-
Pseudokinases are catalytically-deficient
pseudoenzyme variants of
protein kinases that are
represented in all
kinomes across the
kingdoms of life. Pseudokinases...
-
Mixed lineage kinase domain like
pseudokinase (MLKL) is a
protein that in
humans is
encoded by the MLKL gene. This gene
belongs to the
protein kinase superfamily...
-
previously thought to have no
kinase functionality and
accordingly termed a
pseudokinase domain, has
since been
found to be
catalytically active,
albeit at only...
-
Eyers PA, et al. (January 2014). "A
robust methodology to
subclassify pseudokinases based on
their nucleotide-binding properties". The
Biochemical Journal...
- CAMKK2
Pseudokinases are pseudoenzymes,
proteins that
resemble enzymes structurally, but lack
catalytic activity. Some of
these pseudokinases that are...
- known,
conceptually similar to the
kinase and
pseudokinase domain polypeptide structure of the JAK
pseudokinases. A
complete comparative analysis of human...
-
changes in the JAK
protein to
facilitate binding of substrate. JH2 is a
pseudokinase domain, a
domain structurally similar to a
tyrosine kinase and essential...
-
human protein kinases, and
refers to both
protein kinases and
protein pseudokinases and
their evolution of
protein kinases throughout the eukaryotes. Other...
-
Protein kinases can be
classed as
catalytically active (canonical) or as
pseudokinases,
reflecting the
evolutionary loss of one or more of the
catalytic amino...
-
pseudoenzymes in
terms of
cellular signalling functions are
probably the
pseudokinases, the
pseudoproteases and the pseudophosphatases. Recently, the pseudo-deubiquitylases...
