Definition of Protoxins. Meaning of Protoxins. Synonyms of Protoxins

- Protoxin-I, also known as ProTx-I, or Beta/omega-theraphotoxin-Tp1a, is a 35-amino-acid peptide neurotoxin extracted from the venom of the tarantula Thrixopelma...
- Protoxin-II, also known as ProTx-II, PT-II or β/ω-TRTX-Tp2a, is a neurotoxin that inhibits certain voltage-gated calcium and voltage-gated sodium channels...
- research focus has been on the design and characterization of prodrugs and protoxins targeted for activation by cancer specific proteases. This research is...
- in the liver. Parent non-toxic chemicals are generally referred to as protoxins. While toxication is generally undesirable, in certain cases it is required...
- prodrugs are converted into their active metabolites, or the toxication of protoxins into actual toxins. An enzyme may be reversibly or irreversibly bioactivated...
- substances are bioactivated by CYP3A4 to form their active compounds, and many protoxins are toxicated into their toxic forms (see table below for examples). CYP3A4...
- A is biosynthesized as a pyrophosphate containing phosphocalyculin A protoxins by a hybrid PKS-NRPS pathway within the sponge bacterial symbiont, "Candidatus...
- margins 'Violaceum' – younger shoots and branches have bluish color A protoxin present in the seeds of Acer negundo, hypoglycin A, has been identified...
- acute kidney injury. It is not the myoglobin itself that is toxic (it is a protoxin), but the ferrihemate portion that is dissociated from myoglobin in acidic...
- provocation. In 2014, researchers at Yale University identified a toxin called Protoxin-I from the tarantula's venom that shows promise as a new painkiller drug...