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Proteasomes are
protein complexes which degrade ubiquitin-tagged
proteins by proteolysis, a
chemical reaction that
breaks peptide bonds.
Enzymes that...
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Proteasome inhibitors (INN stem –zomib) are
drugs that
block the
action of
proteasomes.
Proteasomes are
large proteins complexes that are used to break...
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Proteasome subunit beta type-5 also
known as 20S
proteasome subunit beta-5 is a
protein that in
humans is
encoded by the PSMB5 gene. This
protein is one...
- prosome,
multicatalytic proteinase (complex), MCP,
proteasome,
large multicatalytic protease,
proteasome organelle,
alkaline protease, 26S protease, tricorn...
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affects proteins in many ways: it can mark them for
degradation via the
proteasome,
alter their cellular location,
affect their activity, and
promote or...
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evolutionarily conserved peptide sequence found at the C‑termini of
several proteasome activators. The "Hb" at the
beginning of its name
denotes a hydrophobic...
-
Proteasome subunit beta type-3, also
known as 20S
proteasome subunit beta-3, is a
protein that in
humans is
encoded by the PSMB3 gene. This
protein is...
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Proteasome accessory factor E (abbreviated PafE, also
known as
bacterial proteasome activator or Bpa) is an ATP-independent
proteasome activator of Mycobacterium...
- In enzymology, a
proteasome ATPase (EC 3.6.4.8) is an
enzyme that
catalyzes the
chemical reaction ATP + H2O ⇌ {\displaystyle \rightleftharpoons } ADP +...
- syndrome. It is in the
class of
medications known as
proteasome inhibitor. It
works by
inhibiting proteasomes,
cellular complexes that
break down proteins. Bortezomib...
