Definition of Proinsulin. Meaning of Proinsulin. Synonyms of Proinsulin

- humans, proinsulin is encoded by the INS gene. The pancreatic islets only secrete between 1% and 3% of proinsulin intact. However, because proinsulin has...
- its signal peptide is removed by signal peptidase to form "proinsulin". As the proinsulin folds, opposite ends of the protein, called the "A-chain" and...
- 31-amino-acid polypeptide that connects insulin's A-chain to its B-chain in the proinsulin molecule. In the context of diabetes or hypoglycemia, a measurement of...
- more peptide hormones. Examples of natural, human prohormones include proinsulin and pro-opiomelanocortin, but the most widespread prohormones in use are...
- a scenario for the action of proinsulin, insulin and insulin-like growth factors Upstream AUGs in embryonic proinsulin mRNA control its low translation...
- through blood work revealing high insulin levels with low C-peptide and proinsulin. The production of glucose is blocked by alcohol. In those who misuse...
- usually made biochemically with low blood glucose, elevated insulin, proinsulin, and C-peptide levels, and confirmed by localizing the tumour with medical...
- As glucose stimulates insulin secretion, it simultaneously increases proinsulin biosynthesis through translational control and enhanced gene transcription...
- mutations Genetic defects in insulin processing or insulin action Defects in proinsulin conversion Insulin gene mutations Insulin receptor mutations Exocrine...
- created as a precursor form called preproinsulin. This is converted to proinsulin and cleaved by C-peptide to insulin which is then stored in granules in...