Definition of Proinsulin. Meaning of Proinsulin. Synonyms of Proinsulin

- humans, proinsulin is encoded by the INS gene. The pancreatic islets only secrete between 1% and 3% of proinsulin intact. However, because proinsulin has...
- its signal peptide is removed by signal peptidase to form "proinsulin". As the proinsulin folds, opposite ends of the protein, called the "A-chain" and...
- 31-amino-acid polypeptide that connects insulin's A-chain to its B-chain in the proinsulin molecule. In the context of diabetes or hypoglycemia, a measurement of...
- more peptide hormones. Examples of natural, human prohormones include proinsulin and pro-opiomelanocortin, but the most widespread prohormones in use are...
- usually made biochemically with low blood glucose, elevated insulin, proinsulin, and C-peptide levels, and confirmed by localizing the tumour with medical...
- the precursor for a protein is often prefixed by pro-. Examples include proinsulin and proopiomelanocortin, which are both prohormones. Protein precursors...
- As glucose stimulates insulin secretion, it simultaneously increases proinsulin biosynthesis through translational control and enhanced gene transcription...
- insulinoma: hypoglycemia occurs with concurrent elevations of insulin, proinsulin and C peptide glucagonoma: the symptoms are not all due to glucagon elevations...
- through blood work revealing high insulin levels with low C-peptide and proinsulin. The production of glucose is blocked by alcohol. In those who misuse...
- synthesized as preproinsulin, which yields proinsulin after the signal peptide has been cleaved. The proinsulin is then cleaved at two positions to yield...