- In biochemistry, a
zymogen (/ˈzaɪmədʒən, -moʊ-/), also
called a
proenzyme (/ˌproʊˈɛnzaɪm/), is an
inactive precursor of an enzyme. A
zymogen requires...
-
formation around the receptor-
proenzyme complex. The more
neutral pH of the
cytosol promotes binding of the
proenzyme's M6P
targeting sequences to their...
-
proenzymes) must be
activated first. This is done by
removing the
amino acid that
blocks the
entrance channel to the
active site when the
proenzyme is...
-
inactivated pepsinogen. Once in the
stomach lumen gastric acid
activates the
proenzyme to pepsin.
Gastric acid
further inhibits the
survival and
progress of...
-
secreted in an
inactive proenzyme form. When
these proenzymes reach the
lumen of the tract, a
factor specific to a
particular proenzyme will
activate it. A...
- Papain-like
cysteine proteinases are
essentially synthesised as
inactive proenzymes (zymogens) with N-terminal
propeptide regions. The
activation process...
-
abundantly represented in sera from
cancer patients. The
presence of
inactive proenzyme forms of PSA is
another potential indicator of disease. PSA
exists in...
-
hydrolyzes proteins.
Trypsin is
formed in the
small intestine when its
proenzyme form, the
trypsinogen produced by the pancreas, is activated. Trypsin...
-
convertase (EC 3.4.21.47,
complement component C3/C5
convertase (alternative),
proenzyme factor B,
properdin factor B, C3 proactivator, glycine-rich beta-glycoprotein...
- of the
plasma proteins (1%) are
regulatory proteins, such as enzymes,
proenzymes, and hormones. All
blood proteins are
synthesized in
liver except for...
