- directly, a
corresponding prodrug can be used to
improve how the drug is absorbed, distributed, metabolized, and
excreted (ADME).
Prodrugs are
often designed...
- Hypoxia-activated
prodrugs are
prodrugs that
target regions of
tumor hypoxia within tumor cells.
These types of
drugs have the potential,
alone and in...
- medicine,
neurotransmitter prodrugs have also been used as
recreational drugs in some cases.
Monoamine neurotransmitter prodrugs include the catecholamine...
- and
includes the
following marketed medications:
Several of
these act as
prodrugs of norethisterone,
including norethisterone acetate,
norethisterone enanthate...
-
Directed enzyme prodrug therapy (DEPT) uses
enzymes artificially introduced into the body to
convert prodrugs,
which have no or poor
biologically activity...
-
prepare ester prodrugs which have
increased half-lives
relative to the
parent compound. The
lipophilicity of the
cypionate group allows the
prodrug to be sequestered...
-
psychedelic of the
tryptamine family. It acts as a
prodrug of
psilocin (4-HO-DMT)
similarly to
other psilocin prodrugs like 4-AcO-DMT, 4-PrO-DMT, and psilocybin...
- His main
research focus has been on the
design and
characterization of
prodrugs and
protoxins targeted for
activation by
cancer specific proteases. This...
- acyl
derivatives was
researched in the 1980s as
injectable water-soluble
prodrugs of alprazolam, but were
never developed for
medical use. Subsequently,...
- levodopa/carbidopa/entacapone). In
addition to
levodopa itself,
certain prodrugs of
levodopa are available,
including melevodopa (melevodopa/carbidopa)...
