- also be
involved in pro-protein
transport and secretion. Pro-domain (or
prodomain) is the
domain of a proprotein. Alberts,
Bruce (2002).
Molecular biology...
- activity. Once in the
acidic environment of the
vacuole or lysosome, the
prodomain is
cleaved off to
reveal the
active enzyme.
Legumain is a
cysteine protease...
- the
autocleavage of the
signal peptide and N-terminal
prodomain,
though the N-terminal
prodomain retains its ****ociation with the
catalytic domain. In...
-
heavily glycosylated and
proteolytically processed to its
mature form. The
prodomain has been
shown to act as an
intramolecular chaperone in the ER, preventing...
-
valine to
methionine exchange at
codon 66, Val66Met,
which is in the
prodomain of BDNF. Val66Met is
unique to humans. The
mutation interferes with normal...
-
Inititator Pro-caspases have a
prodomain that
allows recruitment of
other pro-caspases,
which subsequently dimerise. Both pro-caspase
molecules undergo...
-
consists of two
protein domains, a
disintegrin domain and a
prodomain; however, only the
prodomain is
required for APP processing.
Other ADAM proteins, ADAM17...
-
bound to ADP 2p1h:
Rapid Folding and
Unfolding of Apaf-1 CARD 2ygs: CARD
DOMAIN FROM APAF-1 3ygs: APAF-1 CARD IN
COMPLEX WITH
PRODOMAIN OF PROCASPASE-9...
- (February 2015). "Identification of the
minimum peptide from
mouse myostatin prodomain for
human myostatin inhibition".
Journal of
Medicinal Chemistry. 58 (3):...
- Q, Sage H,
Dempsey P,
Lenhart PM, et al. (December 2007). "The ADAM10
prodomain is a
specific inhibitor of ADAM10
proteolytic activity and
inhibits cellular...
