Definition of Procaspases. Meaning of Procaspases. Synonyms of Procaspases

- Caspases (cysteine-aspartic proteases, cysteine aspartases or cysteine-dependent aspartate-directed proteases) are a family of protease enzymes playing...
- prothrombin, or plasminogen) Some of the proteins of the complement system Procaspases Pacifastin Proelastase Prolipase Procarboxypolypeptidases Enzyme Protein...
- apoptosis signalling molecules simultaneously bind multiple procaspases. The procaspases transactivate via cleavage, activate additional caspases in the...
- death domain (FADD) translocates with the DISC, allowing recruitment of procaspases 8 and 10. These caspases then activate the effector caspases 3, 6, and...
- inhibits the close interaction of the procaspases to one another. Without this close proximity, the procaspases cannot be completely cleaved and remain...
- mitochondria. Releasing of cytochrome c from the IMS to the cytosol activates procaspases and triggers a caspase cascade leading to apoptosis. The intermembrane...
- the ground state apoptosome. Once apoptosome binds to procaspase-9, the Apaf-1 CARDs and procaspase-9 CARDs form a flexible disk-like structure sitting...
- present as zymogens, termed procaspases, which are inactive until a biochemical change causes their activation. Each procaspase has an N-terminal large subunit...
- apoptosis signalling molecules simultaneously bind multiple procaspases. The procaspases transactivate via cleavage, activate additional caspases in the...
- signal be received. In parallel, these enzymes activate proapoptotic procaspase-8, which does directly activate the mitochondrial events of apoptosis...