-
deliver nucleotide analogues (as monophosphate) into the cell (
ProTide:
PROdrug + nucleo
TIDE). This
technology was
invented by
Professor Chris McGuigan from...
-
barrier to the
development of resistance.
Sofosbuvir is a
prodrug of the
Protide type,
whereby the
active phosphorylated nucleotide is
granted cell permeability...
-
prodrug of tenofovir. It was
developed by
Gilead Sciences based on the
protide technology of
Chris McGuigan and is
applied in the form of
tenofovir alafenamide...
- have a
diurnal tide—one high and low
tide each day. A "mixed
tide"—two
uneven magnitude tides a day—is a
third regular category.
Tides vary on timescales...
-
electronegative atoms with open lone pairs.
Hydrides containing protium are
known as
protides.
Hydrides containing deuterium are
known as deuterides. Some deuterides...
- 2007.03.029 Z. P. Li, B. H. Liu. K. Arai, N. Morigazaki, S. Suda (2003): "
Protide compounds in
hydrogen storage systems".
Journal of
Alloys and Compounds...
-
general name
referring to the
negative ion of any
hydrogen isotope (H−)
Protide: 1H− Deuteride: 2H−, D − Tritide: 3H−, T −
Hydrogen ions
drive ATP synthase...
- sign of
inflammation or
damage to
cells in the liver.
Remdesivir is a
protide (prodrug of nucleotide) able to
diffuse into cells,
where it is converted...
- 029. Li, Z.P.; Liu, B.H.; Arai, K.; Morigazaki, N.; Suda, S. (2003). "
Protide compounds in
hydrogen storage systems".
Journal of
Alloys and Compounds...
- in cells. Additionally, the
monophosphate prodrugs of
kinetin riboside,
ProTides, also
showed activation of PINK1. In
December 2017, niclosamide, an anthelmintic...
