-
Pretomanid is an
antibiotic medication used for the
treatment of multi-drug-resistant
tuberculosis affecting the lungs. It is
generally used
together with...
- PA-824 (now
pretomanid), OPC-67683 (now delamanid), and R207910 (now bedaquiline), all of
which are in
Phase II of development.
Pretomanid and delamanid...
-
variety include metronidazole, tinidazole, nimorazole, dimetridazole,
pretomanid, ornidazole, megazol, and azanidazole.
Drugs based on 2-nitroimidazoles...
-
August 2019, the Food and Drug
Administration (FDA)
approved the use of
pretomanid in
combination with
bedaquiline and
linezolid for
treating a
limited and...
-
Morinamide J04AK05
Bedaquiline J04AK06
Delamanid J04AK07
Amithiozone J04AK08
Pretomanid J04AM01
Streptomycin and
isoniazid J04AM02
Rifampicin and
isoniazid J04AM03...
-
shown to be
important in the
action of
another antimycobacterial prodrug pretomanid.
Isoniazid is
bactericidal to
rapidly dividing mycobacteria, but is bacteriostatic...
- to
which mycolic acid
would be attached. This
mechanism is
shared with
pretomanid.
Clinical isolates resistant to this drug tend to have
mutations in the...
-
component of the
experimental BPaMZ combination treatment (bedaquiline +
pretomanid +
moxifloxacin + pyrazinamide). "Bedaquiline Fumarate". The
American Society...
-
trial or on a comp****ionate basis.
Their efficacy and
safety are unknown:
Pretomanid (manufactured by Novartis,
developed in
partnership with TB Alliance)...
- Rare
pediatric Zolgensma Spinal muscular atrophy AveXis Tropical disease Pretomanid Tuberculosis TB
Alliance Material threat countermeasure Jynneos Smallpox...
