- modifications,
preprotachykinins produce multiple peptide neurotransmitters.
There are two
human preprotachykinins:
preprotachykinin-1 (also PPT-1, PPT-I...
-
Preprotachykinin-1, (abbreviated PPT-1, PPT-I, or PPT-A), is a
precursor protein that in
humans is
encoded by the TAC1 gene. The
protein has four isoforms—alpha-...
-
produced from a
polyprotein precursor after alternative splicing of the
preprotachykinin A gene. The
deduced amino acid
sequence of
substance P is as follows:...
-
neurokinin A as the
final post-translational
processing product of beta-
preprotachykinin. Like
neurokinin A,
neuropeptide K has been
localized to
sensory neurons...
- The
genes that
produce tachykinins encode precursor proteins called preprotachykinins,
which are
chopped apart into
smaller peptides by posttranslational...
-
segments in the TAC3 gene
encode for the NKB
precursor known as
preprotachykinin B.
Preprotachykinin B is then
proteolytically cleaved into the pro-peptide proneurokinin...
-
Among them, some have
specific role in the
nervous system such as the
preprotachykinin-1 gene,
giving rise to
substance P and
neurokinin A and the choline...
-
effects of
cocaine and
methamphetamine on neurotensin/neuromedin N and
preprotachykinin messenger RNA
expression in
unique regions of the striatum". Neuroscience...
- pain and the
inflammatory responses. It is
produced from the same
preprotachykinin A gene as the
neuropeptide substance P. Both
substance P and neurokinin...
