-
Prenylation (also
known as
isoprenylation or lipidation) is the
addition of
hydrophobic molecules to a
protein or a biomolecule. It is
usually ****umed...
-
transmembrane domain. One form of C-terminal
modification is
prenylation.
During prenylation, a farnesyl- or geranylgeranyl-isoprenoid
membrane anchor is...
- of the protein. This
prenylation of
lipid chains to
proteins facilitate their interaction with the cell membrane. The
prenylation motif “CaaX box” is the...
-
pyrophosphate and
geranylgeranyl pyrophosphate.
Inhibition of
protein prenylation for
proteins such as RhoA (and
subsequent inhibition of Rho-****ociated...
- PMID 20962881.
Magee T,
Seabra MC (April 2005). "Fatty
acylation and
prenylation of proteins: what's hot in fat".
Current Opinion in Cell Biology. 17...
-
Geranylgeranylation is a form of
prenylation,
which is a post-translational
modification of
proteins that
involves the
attachment of one or two 20-carbon...
- beta (IL-1β) in MKD, most
likely mediated by
defective protein prenylation.
Prenylation refers to
addition of
hydrophobic isoprenoids to proteins, such...
- to its
prenylation and
palmitoylation (HRAS and NRAS) or the
combination of
prenylation and a
polybasic sequence adjacent to the
prenylation site (KRAS)...
- as well as in
modulating protein–protein interactions. In
contrast to
prenylation and myristoylation,
palmitoylation is
usually reversible (because the...
-
lipid metabolism (sphingolipids,
fatty acids), apoptosis, autophagy, and
prenylation of proteins; the mode of
action of
oxysterols in
these effects is still...
