Definition of Premutation. Meaning of Premutation. Synonyms of Premutation

- A premutation is a situation in which there are an excess number of repeats in a gene that is at risk of increasing in length during reproduction but...
- with more than 200. A premutation is said to be present when the gene has between 55 and 200 repeats; females with a premutation have an increased risk...
- a late-onset neurodegenerative disorder most frequently seen in male premutation carriers of Fragile X syndrome (FXS) over the age of 50. The main clinical...
- About 1:150-1:200 women in the US po****tion carry a premutation. Women who carry an FMR1 premutation have a roughly 20% risk of being diagnosed with FXPOI...
- disease, developmental delays and other cognitive deficits. The FMR1 premutation is ****ociated with a wide spectrum of clinical phenotypes that affect...
- mutation, called the 'premutation', doesn't cause any clinical symptoms. A second mutation was required to convert the 'premutation' into a 'full mutation'...
- factors, radiation, or surgery in 10%. Two to 5% of women with POI and a premutation in FMR1, a genetic abnormality, are at risk of having a child with fragile...
- progeny can progress to premutation and ultimately affected status. Individuals with a number of repeats that falls in the premutation range have a good chance...
- 2014). "****ociation between macroorchidism and intelligence in FMR1 premutation carriers". American Journal of Medical Genetics Part A. 164 (9): 2206–2211...
- F, et al. (August 1997). "The Friedreich ataxia GAA triplet repeat: premutation and normal alleles". Human Molecular Genetics. 6 (8): 1261–6. doi:10...