- of 5β-
pregnane compounds.
Pregnanes are
steroid derivatives with
carbons present at
positions 1
through 21. Most
biologically significant pregnane derivatives...
-
virilization of the male fetus.
Allopregnanolone is an
endogenous inhibitory pregnane neurosteroid. It is made from pregnenolone, and is a
positive allosteric...
-
Lehmann JM (January 1998). "An
orphan nuclear receptor activated by
pregnanes defines a
novel steroid signaling pathway". Cell. 92 (1): 73–82. doi:10...
- allopregnanedione): 5α-
pregnane-3,20-dione –
GABAA receptor positive allosteric modulator 5β-Dihydroprogesterone (5β-DHP; pregnanedione): 5β-
pregnane-3,20-dione –...
- androgens. This
process starts with 21-carbon (C 21) steroids, also
known as
pregnanes, and
involves a step
called "5α-reduction". Notably, this
pathway does...
- derivatives. It is one of the
epimers of
pregnane, the
other being 5α-
pregnane.
Derivatives of 5β-
pregnane include the
naturally occurring steroids...
- C19-steroids for the
androstanes (mostly androgens), and C21-steroids for the
pregnanes (mostly corticosteroids). The
classification "17-ketosteroid" is also...
-
Meclizine Nigramide J
Okadaic acid PK-11195 S-07662 T-0901317
PXRTooltip Pregnane X
receptor Agonists: 17α-Hydroxypregnenolone 17α-Hydroxyprogesterone Δ4-Androstenedione...
- of the
human pregnane X receptor,
albeit with an EC50 that is more than an
order of
magnitude lower than that of
other endogenous pregnanes like pregnenolone...
- as an
agonist ligand for the
nuclear receptor farnesoid X
receptor and
pregnane X receptor,
blocking cholesterol homeostasis. Thus
cafestol can increase...
