Definition of Prefusion. Meaning of Prefusion. Synonyms of Prefusion

- constructs to identify the most immunogenic, and constructed a bivalent RSV prefusion F investigational vaccine. In February 2023, results of a phase III study...
- independently of G. F protein exists in multiple conformational forms. In the prefusion state (PreF), the protein exists in a trimeric form and contains the major...
- exists in two conformations: a metastable prefusion form and a stable postfusion form, with the prefusion form being a major target for neutralizing...
- Structure of the Porcine Epidemic Diarrhea Virus Spike Protein in the Prefusion Conformation". Journal of Virology. 93 (23). doi:10.1128/JVI.00923-19...
- of parti****nts in clinical trial NCT02878330. Nirsevimab binds to the prefusion conformation of the RSV fusion (F) protein, i.e. it binds to the site...
- synthetic vaccines use a 2P mutation to lock the spike protein into its prefusion configuration, stimulating an adaptive immune response to the virus before...
- McLellan JS (March 2020). "Cryo-EM structure of the 2019-nCoV spike in the prefusion conformation". Science. 367 (6483): 1260–1263. Bibcode:2020Sci...367.1260W...
- shape after, known as the prefusion and postfusion conformations. Antibodies that recognize spike proteins in the prefusion shape are much more effective...
- Lusine; Hulstrøm, Veronica (16 February 2023). "Respiratory Syncytial Virus Prefusion F Protein Vaccine in Older Adults". New England Journal of Medicine. 388...
- substitutions (K986P and V987P, designated "2P") that cause the spike to adopt a prefusion-stabilized conformation reducing the membrane fusion ability, increasing...