- This
inhibition by (p)
ppGpp decreases translation in the cell,
conserving amino acids present. Furthermore,
ppGpp and ppp
Gpp cause the up-regulation...
- and
trigger the
synthesis of the
guanosine pentaphosphate ((p)
ppGpp) molecule. (p)
ppGpp biosynthesis is a part of the
purine metabolism pathway and coordinates...
-
Generalized pustular psoriasis Gross Primary Productivity Gpp protein,
which converts ppp
Gpp to
ppGpp during the
stringent response Geranyl pyrophosphate 3GPP...
- (p)
ppGpp synthase/hydrolase SpoT or SpoT is a
regulatory enzyme in the RelA/SpoT
Homologue (RSH)
protein family that
synthesizes and
hydrolyzes (p)
ppGpp...
- into ppp
Gpp by
adding the
pyrophosphate from ATP onto the 3'
carbon of the
ribose in GTP,
releasing AMP. ppp
Gpp is
converted to
ppGpp by the
gpp gene product...
- aminoacyl-tRNA
binding site of ribosomes,
triggering the
formation of (p)
ppGpp,
which in turn
inhibits RNA synthesis. The
combined inhibition of protein...
- the
stringent response factor,
guanosine 5'-diphosphate 3'-diphosphate (
ppGpp), a
second messenger in
bacterial cells.
Polyphosphates parti****te in the...
- RSH
superfamily Members share capability to
hydrolyze and/or
synthesize ppGpp alarmones in the
stringent response.
Serpin superfamily Members share a...
-
ribosomes and
catalyzing the reaction: GTP + ATP --> ppp
Gpp + AMP The γ-phosphate is then
removed and
ppGpp will bind to and
inhibit RNA polymerase. This binding...
-
converted to 5´-diphosphate 3´-diphosphate
guanosine (
ppGpp), the
archetypical alarmone.
ppGpp will bind to RNA
polymerase β and β´ subunits, changing...
