- In
clinical terms, a
potentiator is a
reagent that
enhances sensitization of an antigen.
Potentiators are used in the
clinical laboratory for performing...
-
positive allosteric modulators, also
known as
GABAkines or
GABAA receptor potentiators, are
positive allosteric modulator (PAM)
molecules that
increase the...
- PF-04958242
among others. It is a "high-impact"
AMPAR potentiator,
unlike "low-impact"
AMPAR potentiators from
other classes like CX-516 and its
congener farampator...
-
treatment of
cystic fibrosis. It is a
combination of deutivacaftor, a CFTR
potentiator; tezacaftor; and vanzacaftor, as the
calcium salt,
vanzacaftor calcium...
- "Pharmacological
detection of AMPA
receptor heterogeneity by use of two
allosteric potentiators in rat
hippocampal cultures".
British Journal of Pharmacology. 123 (7):...
- CF
mutations the
patient has.
Ivacaftor is a
selective small-molecule
potentiator of the CFTR
protein that
increases the protein's
ability to open chloride...
-
combination of
anatomical reasons, or
Tongue thrusting is the
cause or
potentiator of an open or
incompetent lip state,
which resists efforts at behavioural...
-
protein cannot transport chloride through the channel. Ivacaftor, a CFTR
potentiator,
improves the
transport of
chloride through the ion
channel by binding...
-
Tajima Y,
Yamada R,
Kimura H (December 2021). "TAK-653, an AMPA
receptor potentiator with
minimal agonistic activity,
produces an antidepressant-like effect...
- as
potentiators. RBCs have a net
negative charge called zeta
potential which causes them to have a
natural repulsion for one another.
Potentiators reduce...
