-
proteins L40 and S27a, respectively. The UBB and UBC
genes code for
polyubiquitin precursor proteins.
Ubiquitylation (also
known as
ubiquitination or...
-
other ligases to
attach additional ubiquitin molecules. The
result is a
polyubiquitin chain that is
bound by the proteasome,
allowing it to
degrade the tagged...
- and are
instead united by
molecular phylogenies of rRNA and
actin or
polyubiquitin. They were the
first major eukaryotic group to be
recognized mainly...
-
Polyubiquitin-C is a
protein encoded by the UBC gene in humans.
Polyubiquitin-C is one of the
sources of ubiquitin,
along with UBB, UBA52, and RPS27A...
-
conjugate ubiquitin in a head-to-tail
manner to
generate linear (M1-linked)
polyubiquitin chains. The
complex is
currently known to be
composed of
three proteins:...
-
compartments within the cell. BRCA1 polypeptides, in particular, Lys-48-linked
polyubiquitin chains are dis****d
throughout the
resting cell nucleus, but at the...
-
possesses a UBA domain,
alongside the UBX domain, that
could interact with
polyubiquitin chains. Additionally, it
possesses a UAS
domain of
undetermined function...
-
molecules to
lysine residues of the
previously attached ubiquitin, a
polyubiquitin chain is formed. A
polyubiquitinated protein is
produced and this is...
- example, the E3
ligase MDM2
ubiquitylates p53
either for
degradation (K48
polyubiquitin chain), or for
nuclear export (monoubiquitylation).
These events occur...
- ubiquitin-conjugating
enzyme (ubiquitin E2 ligase)
complex attaches K63-linked
polyubiquitin chains to some of IL-1signaling intermediates, for
instance TGF-β-activated...
