-
polypeptide known as a
polyprotein that
requires proteolytic cleavage into
individual smaller polypeptide chains. The
polyprotein pro-opiomelanocortin (POMC)...
- ORF1a
followed by ORF1b. The
polyproteins have
their own proteases,
PLpro (nsp3) and 3CLpro (nsp5),
which cleave the
polyproteins at
different specific sites...
-
viral genome.
Within the
polyprotein is an
enzyme (or enzymes) with
proteinase function that is able to
cleave the
polyprotein into the
various single...
-
layout of 5'–gag–pro–pol–env–3' in the RNA genome. gag and pol
encode polyproteins, each
managing the
capsid and replication. The pol
region encodes enzymes...
-
budding sites.[citation needed] Once Gag is
translated on ribosomes, Gag
polyproteins are
myristoylated at
their N-terminal
glycine residues by N-myristoyltransferase...
- families. 2A
peptides can be
introduced artificially to help
generate polyproteins from a
single ORF, by
causing the
ribosome to fail at
making a peptide...
- the
membrane of the
infected cell. The Gag (p55) and Gag-Pol (p160)
polyproteins also ****ociate with the
inner surface of the
plasma membrane along with...
- long and has a
single open
reading frame encoding a
polyprotein. Host
proteases cut this
polyprotein into
three structural (C, prM, E) and
seven nonstructural...
- nine
genes that
encode fifteen viral proteins.
These are
synthesized as
polyproteins which produce proteins for
virion interior,
called Gag,
group specific...
- the
genome is
translated in a cap-independent
manner into a
single polyprotein,
which is
subsequently processed by virus-encoded
proteases into the...
