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Polyglycylation is a form of
posttranslational modification of
glutamate residues of the carboxyl-terminal
region tubulin in
certain microtubules (e.g...
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Glutamate Carboxylation ADP-ribosylation
Methylation Polyglutamylation Polyglycylation Asparagine Deamidation Glycosylation Glutamine Transglutamination Lysine...
- the same
family lengthen the
polyglutamate chain (TTL6,11 and 13).
Polyglycylation: the
addition of a
glycine polymer (2-10
residues long) to the gamma-carboxyl...
- of
tubulin and some
other proteins. (See
tubulin polyglutamylase)
polyglycylation,
covalent linkage of one to more than 40
glycine residues to the tubulin...
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modifications include detyrosination, acetylation, polyglutamylation,
polyglycylation, phosphorylation, ubiquitination, sumoylation, and palmitoylation....
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however the two of most
regarded interest are
polyglutamylation and
polyglycylation. Both
modifications are
similar in the
sense they are
repeating stretches...
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Schmitter JM, Le Caer JP,
Rossier J,
Adoutte A, Bré MH (December 1994). "
Polyglycylation of tubulin: a
posttranslational modification in
axonemal microtubules"...
- "Evolutionary
divergence of
enzymatic mechanisms for
posttranslational polyglycylation". Cell. 137 (6): 1076–1087. doi:10.1016/j.cell.2009.05.020. PMID 19524510...
- they do not
contain much
detyrosinated tubulin.
Polyglutamylation Polyglycylation Acetylation Vasohibins/SVBP are
tubulin carboxypeptidases (TCPs) that...