Definition of Polyglutamylation. Meaning of Polyglutamylation. Synonyms of Polyglutamylation

Here you will find one or more explanations in English for the word Polyglutamylation. Also in the bottom left of the page several parts of wikipedia pages related to the word Polyglutamylation and, of course, Polyglutamylation synonyms and on the right images related to the word Polyglutamylation.

Definition of Polyglutamylation

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Meaning of Polyglutamylation from wikipedia

- Polyglutamylation is a form of reversible posttranslational modification of glutamate residues seen for example in alpha and beta tubulins, nucleosome...
- acetylation in the structure and function of microtubules remains elusive. Polyglutamylation: the addition of a glutamate polymer (typically 4-6 residues long)...
- methotrexate exists. Although the mechanism is not very clear, the polyglutamylation of methotrexate and dihydrofolate in malignant cells is considered...
- ADP-ribosylation Glutamate Carboxylation ADP-ribosylation Methylation Polyglutamylation Polyglycylation Asparagine Deamidation Glycosylation Glutamine Transglutamination...
- formation amino acid addition arginylation, a tRNA-mediation addition polyglutamylation, covalent linkage of glutamic acid residues to the N-terminus of tubulin...
- translational modifications; however the two of most regarded interest are polyglutamylation and polyglycylation. Both modifications are similar in the sense they...
- proteins. These modifications include detyrosination, acetylation, polyglutamylation, polyglycylation, phosphorylation, ubiquitination, sumoylation, and...
- GARFT and thymidylate synthase. Raltitrexed is fully active after polyglutamylation, which allows cellular retention of the drug. By inhibiting Thymidylate...
- dendritic TTLL6 (Tubulin polyglutamylase TTLL6), which elevates the polyglutamylation status of the neurotubules in dendrites. Because spastin displays...
- PMC 65034. PMID 11752472. Cherest H, Thomas D, Surdin-Kerjan Y (2000). "Polyglutamylation of folate coenzymes is necessary for methionine biosynthesis and maintenance...