Definition of Polyglutamine. Meaning of Polyglutamine. Synonyms of Polyglutamine

- A polyglutamine tract or polyQ tract is a portion of a protein consisting of a sequence of several glutamine units. A tract typically consists of about...
- olivopontocerebellar atrophy.[citation needed] There have been reported cases where a polyglutamine expansion may lengthen when p****ed down, which often can result in an...
- with the trinucleotide repeat CAG. These often are translated into polyglutamine-containing proteins that form inclusions and are toxic to neuronal cells...
- caused by polyglutamine expansion, including Huntington's disease and six types of spinocerebellar ataxia.   Common characteristics of polyglutamine (or polyQ)...
- its mutant (polyglutamine expanded) form, the protein is more prone to cleavage that creates shorter fragments containing the polyglutamine expansion....
- Mutants of ataxin 1 with a polyglutamine expansion cause SCA1. Ataxin 2, coded by ATXN2. It is known to cause SCA2 with polyglutamine expansion. Ataxin 3, coded...
- caused by polyglutamine and polyalanine expansion mutations, as frame shifting of the original SCA3 gene product encoding CAG/polyglutamines to GCA/polyalanines...
- disorder, HD has links to problems with neurodevelopment. HD is caused by polyglutamine tract expansion in the huntingtin gene, resulting in the mutant huntingtin...
- spinocerebellar degeneration caused by an expansion of a CAG repeat encoding a polyglutamine tract in the atrophin-1 protein. It is also known as Haw River syndrome...
- androgen receptor's polyglutamine tract called a trinucleotide repeat expansion. SBMA results when the length of the polyglutamine tract exceeds 40 repetitions...