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Polyclonal antibodies (pAbs) are
antibodies that are
secreted by
different B cell
lineages within the body (whereas
monoclonal antibodies come from a single...
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Polyclonal B cell
response is a
natural mode of
immune response exhibited by the
adaptive immune system of mammals. It
ensures that a
single antigen is...
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lymphoproliferative or
autoimmune disorders (e.g., anti-CD20 monoclonals).
Heterologous polyclonal antibodies are
obtained from the
serum of
animals (e.g., rabbit, horse)...
- or
polyclonal IgM
proteins involved in
Types II and III
cryoglobulinemic disease have
rheumatoid factor activity. That is, they bind to
polyclonal immunoglobulins...
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Persistent polyclonal B-cell
lymphocytosis (PPBL) is an
anomaly of the
human immune system characterized by
mildly elevated levels of
white blood cells...
- sample); it can be
either type 2 (monoclonal IgM to
polyclonal IgG) or type 3 (
polyclonal IgM to
polyclonal IgG) cryoglobulin.
Although predominantly encountered...
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Normal blood serum contains a
range of
antibodies and are said to be
polyclonal,
whereas serum from a
person with
plasmacytoma may show a
monoclonal spike...
-
being derived from one
source or the other. Thus
there are
terms like
polyclonal—derived from many clones; oligoclonal—derived from a few clones; and monoclonal—derived...
- immunoglobulin, if not
otherwise noted,
consists of a
variety of
different IgG (
polyclonal IgG). In contrast,
monoclonal antibodies are
identical antibodies produced...
- CA also
occurs in many
healthy individuals;
these nonpathogenic CA are
polyclonal, have low
thermal amplitude, and are
present in low titers, not higher...
