-
Polyadenylation is the
addition of a poly(A) tail to an RNA transcript,
typically a
messenger RNA (mRNA). The poly(A) tail
consists of
multiple adenosine...
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Regulatory regions within the 3′-untranslated
region can
influence polyadenylation,
translation efficiency, localization, and
stability of the mRNA. The...
- of a
mature mRNA
molecule occurs in 3 steps:
Capping of the 5' end
Polyadenylation of the 3' end RNA
Splicing of the
introns During capping, a 7-methylguanosine...
- SV40 is an
abbreviation for
simian vacuolating virus 40 or
simian virus 40, a
polyomavirus that is
found in both
monkeys and humans. Like
other polyomaviruses...
-
Cleavage and
polyadenylation specificity factor (CPSF) is
involved in the
cleavage of the 3'
signaling region from a
newly synthesized pre-messenger RNA...
- CPEB, or
cytoplasmic polyadenylation element binding protein, is a
highly conserved RNA-binding
protein that
promotes the
elongation of the polyadenine...
-
early stop codon, which, upon translation,
produces a
shorter protein.
Polyadenylation is the
covalent linkage of a
polyadenylyl moiety to a
messenger RNA...
- tail. The
cleavage and
adenylation reactions occur primarily if a
polyadenylation signal sequence (5'- AAUAAA-3') is
located near the 3' end of the pre-mRNA...
- The
cytoplasmic polyadenylation element (CPE) is a
sequence element found in the 3'
untranslated region of
messenger RNA.
While several sequence elements...
- The U1A
polyadenylation inhibition element (PIE) is an RNA
element which is
responsible for the
regulation of the
length of the
polyA tail of the U1A...