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Podocin is a
protein component of the
filtration slits of podocytes.
Glomerular capillary endothelial cells, the
glomerular ba****t
membrane and the...
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correct function of the slit
diaphragm include nephrin, NEPH1, NEPH2,
podocin, CD2AP. and FAT1.
Small molecules such as water, glucose, and
ionic salts...
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formation during development and
repair in
pathology affecting podocytes.
Podocin may
interact with
nephrin to
guide it onto
lipid rafts in podocytes, requiring...
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spanned by slit
diaphragms consisting of a mat of proteins,
including podocin and nephrin. In addition, foot
processes have a
negatively charged coat...
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contributes to the
filtration barrier; NPHS2,
which encodes the
protein podocin found in podocytes; and INF2,
which encodes the actin-binding
protein formin...
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proteins are
expressed in the
different compartments of the
kidney with
podocin and
nephrin expressed in glomeruli,
Solute carrier family protein SLC22A8...
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Podocin is a
protein that in
humans is
encoded by the NPHS2 gene. NPHS2 has been
shown to
interact with
Nephrin and CD2AP.
Focal segmental glomerulosclerosis...
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accounting for 40-80% of cases. NPHS2: This gene
encodes for the
protein podocin.
Patients with this
genetic mutation develop nephrotic syndrome in the...
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cytoplasmic domains of
these proteins interact with the C
terminus of
podocin (NPHS2; MIM 604766). NEPH1 is
expressed in
filtration slits of
kidney podocytes...
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Saleem MA, Faul C, Kriz W, Shaw AS,
Holzman LB,
Mundel P (Dec 2001). "
Podocin, a raft-****ociated
component of the
glomerular slit diaphragm, interacts...
