-
Pleuromutilin and its
derivatives are
antibacterial drugs that
inhibit protein synthesis in
bacteria by
binding to the
peptidyl transferase component...
- ATC code J01
Antibacterials for
systemic use is a
therapeutic subgroup of the
Anatomical Therapeutic Chemical classification System, a
system of alphanumeric...
-
antibiotics such as macrolides, chloramphenicol, clindamycin, and the
pleuromutilins. It
includes the 5S
ribosomal RNA and 23S
ribosomal RNA.
Despite having...
- in the 23S rRNA of the
ribosome and
inhibits peptide bond formation.
Pleuromutilins also bind to the
peptidyl transferase center.
Macrolide antibiotics...
- polymyxins,
cephalosporins and
other β-lactam antibiotics, macrolides,
pleuromutilins, glycopeptides, rifamycins, lincosamides, streptogramins, and phosphonic...
-
targeting bacterial ribosomes). FDA
approved on 2
October 2018. Lefamulin:
pleuromutilin antibiotic. FDA
approved on 19
August 2019.
Brilacidin (PMX-30063):...
- Sorensen, E. J. (2011). "A
concise synthesis of the
molecular framework of
pleuromutilin". Chem. Commun. 47 (5): 1500–1502. doi:10.1039/C0CC04077K. PMC 3156455...
-
active against C.
acnes bacteria,
including quinolones, cephalosporins,
pleuromutilins, penicillins, and sulfonamides. The
emergence of antibiotic-resistant...
-
Tiamulin (previously thiamutilin) is a
pleuromutilin antibiotic drug that is used in
veterinary medicine particularly for pigs and poultry.
Tiamulin is...
- nausea, pain at the site of injection, and
liver inflammation. It is a
pleuromutilin antibiotic that
inhibits the
large subunit of
bacterial ribosomes. Lefamulin...
