-
Pleuromutilin and its
derivatives are
antibacterial drugs that
inhibit protein synthesis in
bacteria by
binding to the
peptidyl transferase component...
- ATC code J01
Antibacterials for
systemic use is a
therapeutic subgroup of the
Anatomical Therapeutic Chemical classification System, a
system of alphanumeric...
- nausea, pain at the site of injection, and
liver inflammation. It is a
pleuromutilin antibiotic that
inhibits the
large subunit of
bacterial ribosomes. Lefamulin...
-
Tiamulin (previously thiamutilin) is a
pleuromutilin antibiotic drug that is used in
veterinary medicine particularly for pigs and poultry.
Tiamulin is...
- in the 23S rRNA of the
ribosome and
inhibits peptide bond formation.
Pleuromutilins also bind to the
peptidyl transferase center.
Macrolide antibiotics...
-
antibiotics such as macrolides, chloramphenicol, clindamycin, and the
pleuromutilins. It
includes the 5S
ribosomal RNA and 23S
ribosomal RNA.
Despite having...
-
targeting bacterial ribosomes). FDA
approved on 2
October 2018. Lefamulin:
pleuromutilin antibiotic. FDA
approved on 19
August 2019.
Brilacidin (PMX-30063):...
- polymyxins,
cephalosporins and
other β-lactam antibiotics, macrolides,
pleuromutilins, glycopeptides, rifamycins, lincosamides, streptogramins, and phosphonic...
-
ribosome subunit,
overlapping with the
binding sites of the oxazolidinone,
pleuromutilin, and
macrolide antibiotics,
among others. The
binding is reversible...
-
Disease treatment, prevention, and
growth High
Lincosamide Disease treatment High
Pleuromutilin Growth Not
Polypeptide Growth Not
Carbadox Growth Not...