- gene that has such
multiple effects is
referred to as a
pleiotropic gene.
Mutations in
pleiotropic genes can
impact several traits simultaneously, often...
- when
determining phenotypic outcomes.
Multiple alleles,
epistasis and
pleiotropic genes are some
factors that
might influence the
phenotypic outcome. Although...
-
trials suggest nonspecific effects of
influenza vaccination,
known as
pleiotropic effects, with
broader impact beyond protecting against influenza infection...
-
observed in
Irish and
African people. He
attributes the
epicanthic fold to
pleiotropic genes that
control more than one
characteristic or function. He also...
-
atherosclerotic plaques.
Steroid drugs, such as
prednisone and prednisolone, have
pleiotropic effects,
including systemic ones, for the same
reason that endogenous...
- Pdr1p (
Pleiotropic Drug
Resistance 1p) is a
transcription factor found in
yeast and is a key
regulator of
genes involved in
general drug response. It...
-
Defais M (October 1997). "Mammalian Rad51 protein: a RecA
homologue with
pleiotropic functions". Biochimie. 79 (9–10): 587–92. doi:10.1016/S0300-9084(97)82007-X...
- As the name indicates, this
receptor interacts with interleukin-2, a
pleiotropic cytokine which plays an
important role in
immune homeostasis. The human...
-
Interleukin 16 is a pro-inflammatory
pleiotropic cytokine. Its precursor, pro-interleukin-16 is a
protein that in
humans is
encoded by the IL16 gene....
-
symptom but is now not
regarded as such. Bardet–Biedl
syndrome is a
pleiotropic disorder with
variable expressivity and a wide
range of
clinical variability...