-
Pitolisant, sold
under the
brand name
Wakix among others, is a
medication used for the
treatment of
excessive daytime sleepiness in
adults with narcolepsy...
- the brain.
Pitolisant is an
histamine 3 (H3)-receptor
inverse agonist. As
histamine 3 (H3)
receptors mainly act as autoreceptors,
pitolisant decreases...
- clobenpropit, ABT-239, ciproxifan, conessine, A-349,821, betahistine, and
pitolisant. The
histamine H3
receptor (H3R) was
discovered in 1983 and was one of...
-
These medications include alerting agents (e.g., modafinil, armodafinil,
pitolisant, solriamfetol),
oxybate medications (e.g.,
twice nightly sodium oxybate...
-
histamine release in hypothalamus. An
inverse agonist of the
histamine H3 is
Pitolisant.
Results after testing on
animals have
indicated increased wakefulness...
-
conditions such as long QT syndrome, by
certain medications such as
sotalol or
pitolisant, by
disturbances in the
concentrations of
certain salts within the blood...
- Tetrabe****ne N07XX07
Fampridine N07XX08
Tafamidis N07XX10
Laquinimod N07XX11
Pitolisant N07XX12
Patisiran N07XX13 Valbe****ne N07XX14
Edaravone N07XX15 Inotersen...
-
istradefylline Histamine H3
receptor antagonists and
inverse agonists like
pitolisant and
samelisant Orexin receptor agonists like
danavorexton and suntinorexton...
- or
sodium oxybate (as
first line);
methylphenidate and
pitolisant (as
second line [
pitolisant is
currently only
available in Europe]); and amphetamines...
- agonists:
Loratadine Histamine 3 (H3)
receptor antagonists/inverse agonists:
Pitolisant SERM (selective
estrogen receptor modulators)
Raloxifene Vasodilators...
