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Piromelatine (Neu-P11) is a
multimodal sleep drug
under development by
Neurim Pharmaceuticals. It is an
agonist at
melatonin MT1/MT2 and
serotonin 5-HT1A/5-HT1D...
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results of a
positive phase II
trial of its
investigational compound piromelatine (Neu-P11) in
February 2013. No
antagonists or
selective ligands are currently...
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Fabomotizole (afobazole) GR-196,429
Melatonin N-Acetylserotonin (normelatonin)
Piromelatine Ramelteon Tasimelteon TIK-301 (LY-156,735) Antagonists:
Luzindole MT2Tooltip...
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Fabomotizole (afobazole) GR-196,429
Melatonin N-Acetylserotonin (normelatonin)
Piromelatine Ramelteon Tasimelteon TIK-301 (LY-156,735) Antagonists:
Luzindole MT2Tooltip...
-
Fabomotizole (afobazole) GR-196,429
Melatonin N-Acetylserotonin (normelatonin)
Piromelatine Ramelteon Tasimelteon TIK-301 (LY-156,735) Antagonists:
Luzindole MT2Tooltip...
-
Fabomotizole (afobazole) GR-196,429
Melatonin N-Acetylserotonin (normelatonin)
Piromelatine Ramelteon Tasimelteon TIK-301 (LY-156,735) Antagonists:
Luzindole MT2Tooltip...
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Vornorexant (ORN-0829, TS-142) – dual OX1 and OX2
receptor antagonist [5]
Piromelatine (Neu-P11) –
melatonin receptor agonist and 5-HT1A and 5-HT1D receptor...
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agonists used in
medicine like ramelteon, tasimelteon, agomelatine, and
piromelatine (still in
clinical trials) are
analogues of melatonin. The
first patent...
-
Fabomotizole (afobazole) GR-196,429
Melatonin N-Acetylserotonin (normelatonin)
Piromelatine Ramelteon Tasimelteon TIK-301 (LY-156,735) Antagonists:
Luzindole MT2Tooltip...
-
Fabomotizole (afobazole) GR-196,429
Melatonin N-Acetylserotonin (normelatonin)
Piromelatine Ramelteon Tasimelteon TIK-301 (LY-156,735) Antagonists:
Luzindole MT2Tooltip...