-
Pirfenidone, sold
under the
brand name
Pirespa among others, is a
medication used for the
treatment of
idiopathic pulmonary fibrosis. It
works by reducing...
-
pulmonary rehabilitation and
supplemental oxygen.
Certain medications like
pirfenidone or
nintedanib may slow the
progression of the disease. Lung transplantation...
-
agents intended to
prevent scarring in mild
idiopathic fibrosis are
pirfenidone,
which reduced reductions in the 1-year rate of
decline in FVC and reduced...
- fibrosis) and 6.7
years in
those with
other types of ILD. The
antifibrotics pirfenidone and
nintedanib have been
shown to slow the
decline in lung
function (as...
-
breakthrough therapy designation to
receive FDA approval. 2014:
Esbriet (
pirfenidone): An anti-fibrotic drug for the
treatment of
idiopathic pulmonary fibrosis...
- with IPF,
including those receiving standard of care
treatment with
pirfenidone or nintedanib. However, both
trials were
prematurely terminated due to...
-
idiopathic pulmonary fibrosis,
certain medications like
nintedanib and
pirfenidone can help slow the progression. Lastly, lung
transplants may help. Regardless...
- Sandoval-Rodriguez A, Monroy-Ramirez HC, Meza-Rios A, et al. (March 2020). "
Pirfenidone Is an
Agonistic Ligand for PPARα and
Improves NASH by
Activation of SIRT1/LKB1/pAMPK"...
- Y, Wang Y, Wang C, Tian M, Gu X, Lv W (2021). "Inhibitory
effect of
pirfenidone on
pulmonary fibrosis in
patients with
acute paraquat poisoning". Am...
- analgesia.
Erivedge (vismodegib), for basal-cell carcinoma.
Esbriet (
pirfenidone), for
idiopathic pulmonary fibrosis.
Fansidar (sulfadoxine/pyrimethamine)...
