Definition of Picrotoxin. Meaning of Picrotoxin. Synonyms of Picrotoxin

Here you will find one or more explanations in English for the word Picrotoxin. Also in the bottom left of the page several parts of wikipedia pages related to the word Picrotoxin and, of course, Picrotoxin synonyms and on the right images related to the word Picrotoxin.

Definition of Picrotoxin

Picrotoxin
Picrotoxin Pic`ro*tox"in, n. [Gr. ? bitter + toxic + -in.] (Chem.) A bitter white crystalline substance found in the cocculus indicus. It is a peculiar poisonous neurotic and intoxicant, and consists of a mixture of several neutral substances.

Meaning of Picrotoxin from wikipedia

- Picrotoxin, also known as cocculin, is a poisonous crystalline plant compound. It was first isolated by the French pharmacist and chemist Pierre François...
- convulsant potency was strongly correlated to in vitro affinity to the picrotoxin binding site on the GABAA receptor complex. Many GABAA receptor ligands...
- by interacting with the GABAA receptor-chloride channel complex at the picrotoxin binding site. In humans, lindane affects the nervous system, liver, and...
- काकमारी) is a Southeast Asian and Indian climbing plant. It is the source of picrotoxin, a poisonous compound with stimulant properties. The plant is large-stemmed...
- Clomethiazole acts as a positive allosteric modulator at the barbiturate/picrotoxin site of the GABAA receptor. It works to enhance the action of the neurotransmitter...
- alcohol (ethanol), inhaled anaesthetics, kavalactones, cicutoxin, and picrotoxin, among others. Much like the GABAA receptor, the GABAB receptor is an...
- been recognized that, for neurons that are stimulated by bicuculline and picrotoxin, the fast inhibitory response to GABA is due to direct activation of an...
- Both inhibition by nerve stimulation and by applied GABA are blocked by picrotoxin. GABA is primarily synthesized from glutamate via the enzyme glutamate...
- the GABAA receptor. Its binding site seems to be similar to the one of picrotoxin, a potent neurotoxin and convulsant. The binding of U-93631 decreases...
- included as an effort to wash out the stomach in those with strychnine or picrotoxin poisoning. In the United States the FDA requires tablets of the medication...