- Baozhen; Ding,
Jianping (January 2007). "Crystal
structure of
human phosphoribosylpyrophosphate synthetase 1
reveals a
novel allosteric site".
Biochemical Journal...
-
Amidophosphoribosyltransferase (ATase), also
known as
glutamine phosphoribosylpyrophosphate amidotransferase (GPAT), is an
enzyme responsible for catalyzing...
-
hyperuricemic nephropathy,
medullary cystic kidney disease,
phosphoribosylpyrophosphate synthetase superactivity and hypoxanthine-guanine phosphoribosyltransferase...
- Peng B, Ding J (January 2007). "Crystal
structure of
human phosphoribosylpyrophosphate synthetase 1
reveals a
novel allosteric site". Biochem. J. 401...
- from
shikimic acid or anthranilate:
anthranilate condenses with
phosphoribosylpyrophosphate (PRPP),
generating pyrophosphate as a by-product. The ring of...
-
Ishijima S, Sawa K,
Suzuki N,
Tatibana M (Jan 1997). "The
human phosphoribosylpyrophosphate synthetase-****ociated
protein 39 gene (PRPSAP1) is
located in...
- the
Mechanism of
Phosphoribosylamine Transfer from
Glutamine Phosphoribosylpyrophosphate Amidotransferase to
Glycinamide Ribonucleotide Synthetase". Biochemistry...
-
phosphoribosyltransferase is an
enzyme which creates UMP from
uracil and
phosphoribosylpyrophosphate. This
protein may use the
morpheein model of
allosteric regulation...
- Both TIMP and
MTIMP have been
reported to
inhibit glutamine-5-
phosphoribosylpyrophosphate amidotransferase, the
first enzyme unique to the de novo pathway...
-
distinct but
genetically allelic disorders,
caused by
reduced phosphoribosylpyrophosphate synthetase 1 (PRS1)
activity due to PRPS1 mutations. Only three...
