-
replaces the NR2 moiety.
Phosphoramidites derived from
protected nucleosides are
referred to as
nucleoside phosphoramidites and are
widely used in chemical...
- contrast, in the
presence of even mild acids,
phosphoramidites perish almost instantaneously. The
phosphoramidites are
relatively stable to
hydrolysis under...
-
methyl group led to the
nucleoside phosphoramidites currently used in
oligonucleotide synthesis (see
Phosphoramidite building blocks below). Many later...
- are
widely used in
enantioselective synthesis. The
application of
phosphoramidites as
effective monodentate ligands for
transition metal catalysis was...
-
molecular beacons. The
commercially available 6-FAM
version is
shown in the figure. US 5583236, Brush, C. K., "Fluorescein
Labelled Phosphoramidites" ...
- PMID 36326159. S2CID 253266074. Brush, C. K. "Fluorescein
Labelled Phosphoramidites". U.S.
patent 5,583,236.
Priority date July 19, 1991. Baeyer, Adolf...
-
production of nucleotides. A
purified nucleoside is
protected to
create a
phosphoramidite,
which can then be used to
obtain analogues not
found in
nature and/or...
-
Oligonucleotides are
chemically synthesized using building blocks,
protected phosphoramidites of
natural or
chemically modified nucleosides or, to a
lesser extent...
-
dominant solvent used in
oligonucleotide synthesis from
nucleoside phosphoramidites. Industrially, it is used as a
solvent for the
manufacture of pharmaceuticals...
-
meaning when used in the
context of DNA synthesis:
whereas an
individual phosphoramidite nucleobase to be
added to a DNA
polymer has
protecting groups and has...
