- In enzymology, a
phosphopantothenate—cysteine
ligase also
known as
phosphopantothenoylcysteine synthetase (PPCS) is an
enzyme (EC 6.3.2.5) that catalyzes...
-
equivalents of ATP (see figure).
Pantothenic acid is
phosphorylated to 4′-
phosphopantothenate by the
enzyme pantothenate kinase. This is the
committed step in...
- 4-Phosphopantoate—β-alanine
ligase (EC 6.3.2.36,
phosphopantothenate synthetase, TK1686 protein) is an
enzyme with
systematic name (R)-4-phosphopantoate:beta-alanine...
- (see figure):
Pantothenate (vitamin B5) is
phosphorylated to 4′-
phosphopantothenate by the
enzyme pantothenate kinase (PanK; CoaA; CoaX). This is the...
- + (R)-4-phosphopantoate The
conversion of (R)-pantoate to (R)-4'-
phosphopantothenate is done
during biosynthesis of 4'-phosphopantetheine,.
Yokooji Y...
- spheroids, axon schollen, or
neuroaxonal dystrophy; and Lewy bodies.
Phosphopantothenate has been
shown to
treat PKAN in a
human by
slowing down its progress...
-
Yokooji Y,
Imanaka T, et al. (September 2014). "Crystal
structure of
phosphopantothenate synthetase from
Thermococcus kodakarensis". Proteins. 82 (9): 1924–36...
-
glutathione synthase EC 6.3.2.4: D-alanine—D-alanine
ligase EC 6.3.2.5:
phosphopantothenate—cysteine
ligase (CTP) EC 6.3.2.6: phosphoribosylaminoimidazolesuccinocarboxamide...
- pathway. It
phosphorylates pantothenate (vitamin B5) to form 4'-
phosphopantothenate at the
expense of a
molecule of
adenosine triphosphate (ATP). It...
-
phosphorylated metabolites in
inborn errors of metabolism, such as
phosphopantothenate for PANK2 deficiency,
however these were a
clinical failure. Me****ou...
