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Phospholamban, also
known as PLN or PLB, is a
micropeptide protein that in
humans is
encoded by the PLN gene.
Phospholamban is a 52-amino acid integral...
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releasing the Ca2+ into the SR. A
protein found in
cardiac muscle,
called phospholamban (PLB) has been
shown to
prevent SERCA from working. It does this by...
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effects including phosphorylating phospholamban (via
Protein kinase A).
Phosphorylating phospholamban. When
phospholamban is not phosphorylated, it inhibits...
- and
phosphorylates numerous targets, namely: L-type
calcium channels,
phospholamban,
troponin I,
myosin binding protein C, and pot****ium channels. This...
- (SERCA) by
binding to
transmembrane helices alone or in ****ociation with
phospholamban".
Proceedings of the
National Academy of
Sciences of the
United States...
- up by the mitochondria. An enzyme,
phospholamban,
serves as a
brake for SERCA. At low
heart rates,
phospholamban is
active and
slows down the activity...
- genotype-phenotype ****ociations in DCM and
mutations in
lamin (LMNA),
phospholamban (PLN), RNA
Binding Motif Protein 20 (RBM20),
Cardiac Myosin Binding...
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calcium ATPase (five
different conformations)
Calcium ATPase regulators phospholamban and
sarcolipin ABC
transporters General secretory pathway (Sec) translocon...
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across the SR
membrane can be
controlled by the
regulatory protein phospholamban (PLB/PLN).
SERCA is not as
active when PLB is
bound to it. Increased...
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Perusahaan Listrik Negara,
Indonesian government-owned
electricity company Phospholamban, a
protein Peripheral lymph node Pln, the
abbreviation for the orchid...