- group.
Phosphorylated forms of
phosphatidylinositol (PI) are
called phosphoinositides and play
important roles in
lipid signaling, cell
signaling and membrane...
-
Phosphoinositide 3-kinases (PI3Ks), also
called phosphatidylinositol 3-kinases, are a
family of
enzymes involved in
cellular functions such as cell growth...
- In the
field of biochemistry, PDPK1
refers to the
protein 3-
phosphoinositide-dependent
protein kinase-1, an
enzyme which is
encoded by the PDPK1 gene in...
- PIKfyve, a FYVE finger-containing
phosphoinositide kinase, is an
enzyme that in
humans is
encoded by the
PIKFYVE gene. The prin****l
enzymatic activity...
-
Talaromyces wortmannii, is a non-specific,
covalent inhibitor of
phosphoinositide 3-kinases (PI3Ks). It has an in
vitro inhibitory concentration (IC50)...
- serine/threonine kinase, is
recruited to the
membrane by
interaction with
these phosphoinositide docking sites, so that it can be
fully activated.
Activated Akt mediates...
-
phosphorylates Grb2-****ociated-binding
protein 2 (Gab2),
which binds to
phosphoinositide 3-kinase,
which activates PKC. PKC
leads to the
activation of myosin...
- Ras or Rho
guanosine triphosphatases (Ras or Rho GTPases) and the
phosphoinositide 3-kinases (PI3Ks). In neutrophils,
lipid products of PI3Ks regulate...
- The
enzyme phosphoinositide 5-phosphatase (EC 3.1.3.36)
catalyzes the
reaction 1-phosphatidyl-1D-myo-inositol 4,5-bisphosphate + H2O ⇌ {\displaystyle \rightleftharpoons...
-
brand name Joenja, is a
medication used for the
treatment of
activated phosphoinositide 3-kinase
delta syndrome (APDS). It is a
kinase inhibitor that is taken...
