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Phosphofructokinase (PFK) is a
kinase enzyme that
phosphorylates fructose 6-phosphate in glycolysis. The enzyme-catalysed
transfer of a
phosphoryl group...
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Phosphofructokinase-1 (PFK-1) is one of the most
important regulatory enzymes (EC 2.7.1.11) of glycolysis. It is an
allosteric enzyme made of 4 subunits...
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Phosphofructokinase deficiency is a rare
muscular metabolic disorder, with an
autosomal recessive inheritance pattern. It is
characterized as a deficiency...
- very
potent activator of
phosphofructokinase (PFK-1) that is
synthesized when F6P is
phosphorylated by a
second phosphofructokinase (PFK2). In the liver,...
- include: 6-
phosphofructokinase (pyrophosphate),
inorganic pyrophosphate-dependent
phosphofructokinase,
inorganic pyrophosphate-
phosphofructokinase, pyrophosphate-dependent...
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Phosphofructokinase-2 (6-phosphofructo-2-kinase, PFK-2) or
fructose bisphosphatase-2 (FBPase-2), is an
enzyme indirectly responsible for
regulating the...
- In enzymology, 1-
phosphofructokinase (EC 2.7.1.56) is an
enzyme that
catalyzes the
chemical reaction ATP + D-fructose 1-phosphate → ADP + D-fructose 1...
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working in this way is
fructose 2,6-bisphosphate,
which activates phosphofructokinase 1 and
increases the rate of
glycolysis in
response to the hormone...
- In enzymology, an ADP-specific
phosphofructokinase (EC 2.7.1.146) is an
enzyme that
catalyzes the
chemical reaction ADP + D-fructose 6-phosphate ⇌ {\displaystyle...
- by citrate. High
concentrations of
cytosolic citrate can
inhibit phosphofructokinase, the
catalyst of a rate-limiting step of glycolysis. This effect...
