- In chemistry, a
phosphodiester bond
occurs when
exactly two of the
hydroxyl groups (−OH) in
phosphoric acid
react with
hydroxyl groups on
other molecules...
- to a
nucleophile can
cause a β-elimination reaction,
wherein the 3'
phosphoester bond is broken,
causing a single-stranded break. This
reaction can be...
- and
tyrosine side
chains (in
other words, on
their residues)
through phosphoester bond formation, on histidine,
lysine and
arginine through phosphoramidate...
- the
active catalytic site of the
cholinesterase enzyme. The
resultant phosphoester group is
strongly bound to the cholinesterase, and
irreversibly deactivates...
-
active site.
Fluoride is the
leaving group, and the
resulting organo-
phosphoester is
robust and
biologically inactive. Its
mechanism of
action resembles...
-
Polilactofate (PLF) is a
copolymer of PDLL (poly(d,l-lactide)) and a
phosphoester. It may have
applications in
pharmaceutical delivery. Li, Khan W.; Dang...
- Cysteine-dependent
phosphatases (CDPs)
catalyse the
hydrolysis of a
phosphoester bond via a phospho-cysteine intermediate. The free
cysteine nucleophile...
-
commonly used as
fragrances and
found in
essential oils and pheromones.
Phosphoesters form the
backbone of DNA molecules.
Nitrate esters, such as nitroglycerin...
-
serves to
exclude water from
counterproductively hydrolyzing critical phosphoester bonds while still allowing the
substrate to
access the
active site. Human...
- V.; Voskoboev, A. I.; Burd, V. N. (1
November 2003). "Hydrolysis of
Phosphoester Bond by the Heme-Independent
Chloroperoxidase from
Serratia marcescens"...
