Definition of Pevonedistat. Meaning of Pevonedistat. Synonyms of Pevonedistat

Here you will find one or more explanations in English for the word Pevonedistat. Also in the bottom left of the page several parts of wikipedia pages related to the word Pevonedistat and, of course, Pevonedistat synonyms and on the right images related to the word Pevonedistat.

Definition of Pevonedistat

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Meaning of Pevonedistat from wikipedia

- Pevonedistat (MLN4924) is a selective NEDD8 inhibitor. It is being investigated as a cancer treatment, e.g. for mantle cell lymphoma (MCL). NEDD8-activating...
- repair genes active in alternative pathways (see synthetic lethality). Pevonedistat (MLN4924), a drug inhibiting activation of NEDD8, has shown a significant...
- enzyme is critical for NEDD8 activation. Pevonedistat (MLN4924) is an analog of adenosine sulfamate. Pevonedistat is a mechanism-based inhibitor of NAE....
- abnormal neddylation and cancer, a neddylation inhibitor was developed. Pevonedistat or MLN4929 is the first neddylation E1 inhibitor being tested for several...
- investigator-initiated Phase II clinical trials of MLN4924 (also known as pevonedistat) plus Docetaxel in patients with previously treated advanced non-small...
- discoveries explained how a new experimental anti-cancer drug MLN4924 (Pevonedistat) caused over-replication of the DNA and DNA damage leading to cancer...