-
three classes:
typical 2-cysteine
peroxiredoxins;
atypical 2-cysteine
peroxiredoxins; and 1-cysteine
peroxiredoxins.
These enzymes share the same basic...
-
importance of
peroxiredoxins is
indicated by
their relative abundance (one of the most
abundant proteins in
erythrocytes after hemoglobin is
peroxiredoxin 2). Their...
- ~88 kcal/mol for the (valence)
isoelectronic hydroperoxides, ROOH.
Peroxiredoxins are
ubiquitous and
abundant enzymes that
detoxify peroxides. They function...
- that
combat oxidative stress,
peroxiredoxins play an
important role in
health and disease.
Peroxiredoxin 1 and
peroxiredoxin 2 have been
shown to be released...
- This
enzyme is
involved in
antioxidant metabolism by re-activating
peroxiredoxins,
which are a
group of peroxidases, when
these enzymes are inhibited...
-
include catalase,
glutathione peroxidases, glutathione-S-transferases,
peroxiredoxins,
superoxide di****ases,
thioredoxin reductase and thioredoxins. Deficiencies...
-
response to
oxidative stress.
Evidence for in vivo
overoxidation of
peroxiredoxins at
their active site". J. Biol. Chem. 277 (22): 19396–401. doi:10.1074/jbc...
- (September 2002). "A
method for
detection of
overoxidation of cysteines:
peroxiredoxins are
oxidized in vivo at the active-site
cysteine during oxidative stress"...
-
response to
oxidative stress.
Evidence for in vivo
overoxidation of
peroxiredoxins at
their active site". J. Biol. Chem. 277 (22): 19396–401. doi:10.1074/jbc...
- "Cloning of
bovine peroxiredoxins-gene
expression in
bovine tissues and
amino acid
sequence comparison with rat,
mouse and
primate peroxiredoxins". Comparative...
