-
importance of
peroxiredoxins is
indicated by
their relative abundance (one of the most
abundant proteins in
erythrocytes after hemoglobin is
peroxiredoxin 2). Their...
-
three classes:
typical 2-cysteine
peroxiredoxins;
atypical 2-cysteine
peroxiredoxins; and 1-cysteine
peroxiredoxins.
These enzymes share the same basic...
- that
combat oxidative stress,
peroxiredoxins play an
important role in
health and disease.
Peroxiredoxin 1 and
peroxiredoxin 2 have been
shown to be released...
-
response to
oxidative stress.
Evidence for in vivo
overoxidation of
peroxiredoxins at
their active site". J. Biol. Chem. 277 (22): 19396–401. doi:10.1074/jbc...
-
PeroxiRedoxin classification indEX (PREX) is a
database of
peroxiredoxins (Prxs)
classified into one of six
distinct subfamilies.
classification relies...
- ~88 kcal/mol for the (valence)
isoelectronic hydroperoxides, ROOH.
Peroxiredoxins are
ubiquitous and
abundant enzymes that
detoxify peroxides. They function...
- This
enzyme is
involved in
antioxidant metabolism by re-activating
peroxiredoxins,
which are a
group of peroxidases, when
these enzymes are inhibited...
-
include catalase,
glutathione peroxidases, glutathione-S-transferases,
peroxiredoxins,
superoxide di****ases,
thioredoxin reductase and thioredoxins. Deficiencies...
- reductase.
Antioxidant enzymes, such as
glutathione peroxidases and
peroxiredoxins,
generate glutathione disulfide during the
reduction of
peroxides such...
-
Green EW, Zhao Y, van
Ooijen G,
Olmedo M, Qin X, et al. (May 2012). "
Peroxiredoxins are
conserved markers of
circadian rhythms". Nature. 485 (7399): 459–464...