Definition of Perifosine. Meaning of Perifosine. Synonyms of Perifosine

Here you will find one or more explanations in English for the word Perifosine. Also in the bottom left of the page several parts of wikipedia pages related to the word Perifosine and, of course, Perifosine synonyms and on the right images related to the word Perifosine.

Definition of Perifosine

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Meaning of Perifosine from wikipedia

- Perifosine (also KRX-0401) is a former drug candidate that was under development for a variety of cancer indications. It is an alkyl-phospholipid structurally...
- undergone clinical trials. In 2007 VQD-002 had a phase I trial. In 2010 Perifosine reached phase II. but it failed phase III in 2012. Miltefosine is approved...
- olaparib, rucaparib, niraparib and talazoparib) PI3K inhibitors (e.g. perifosine in a phase III trial) Apatinib is a selective VEGF Receptor 2 inhibitor...
- metabolically stable, and several ALPs such as edelfosine, miltefosine and perifosine are under research and development as drugs against cancer and other diseases...
- cells from bone marrow transplants. It is an analog of miltefosine and perifosine. Edelfosine apoptosis-inducing abilities were studied with several types...
- (INN) Pergonal perhexiline (INN) Periactin periciazine (INN) Peridex perifosine (INN) perimetazine (INN) perindopril (INN) perindoprilat (INN) Periochip...
- shown to inhibit mTORC1, while activating Akt through RICTOR elevation. Perifosine has been shown to interfere with mTOR activity by degrading its components...
- healthy cells. Several examples including edelfosine, miltefosine, and perifosine are under development as drugs against cancer and other diseases. Munder...
- perfusion – perfusion magnetic resonance imaging – pericardial effusion – perifosine – perineal colostomy – perineal prostatectomy – peripheral blood lymphocyte...