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Perforin-1
Perforin (PRF),
encoded by the PRF1 gene, is a pore-forming
toxic protein housed in the
secretory granules of
cytotoxic T
lymphocytes (CTLs)...
-
protein pathway. In this
pathway perforins and
granzymes are
taken up by the
target cell. In this pathway, the
perforins facilitate the
entry of granule...
-
chemokines (IP-10, lymphotactin),
trigger cytolysis of
target cells (
perforins, granzymes...), and
interact with
other cells, such as
epithelial cells...
- patients.
Presence of
multiple uncleared viral infections due to lack of
perforin are
thought to be responsible. In
addition to
chronic and/or recurrent...
- be
triggered by
activated T
cells –
which secrete toxic granzymes and
perforin – or
indirectly as a
result of
reduced blood flow or the
generation of...
- FHL are each ****ociated with a
specific gene: FHL1: HPLH1 FHL2: PRF1 (
Perforin) FHL3: UNC13D (Munc13-4) FHL4: STX11 (Syntaxin 11) FHL5: STXBP2 (Syntaxin...
-
protection Pentafluorophenyl esters Perfluoropentacene (organic semiconductor)
Perforin (formerly PFP gene)
Photoelectric flame photometer Plutonium Finishing...
- cells. It is
secreted by
these cells along with the pore
forming protein perforin to
mediate apoptosis in
target cells.
Granzyme B has also been
found to...
- The
Membrane Attack Complex/
Perforin (MACPF) superfamily,
sometimes referred to as the MACPF/CDC superfamily, is
named after a
domain that is
common to...
-
conjugation triggers degranulation and
release of
cytotoxic granules containing perforin and
granzymes to kill antibody-sensitized
target cells. "B Cell Development...
