-
information that
replaces the
targeted sequence. The
pegRNA consists of an
extended single guide RNA (sg
RNA)
containing a
primer binding site (PBS) and a reverse...
-
nucleic acid
lipid particles (SNALPs) used to
package si
RNA for use in vivo. In
blood banking,
PEG is used as a
potentiator to
enhance detection of antigens...
-
converts a
single nucleotide into another. The new guide,
called a
pegRNA,
contains an
RNA template for a new DNA
sequence to be
added to the
genome at the...
-
editing system,
which uses Cas9
nickase and the
prime editing guide RNA (
pegRNA)
carrying the
target genes. One
limitation of
current technology is that...
- DMG-
PEG 2000 is a
synthetic lipid formed by the
PEGylation of
myristoyl diglyceride. It is used to
manufacture lipid nanoparticles that are used in m
RNA vaccines...
-
covalent and non-covalent
attachment or
amalgamation of
polyethylene glycol (
PEG, in
pharmacy called macrogol)
polymer chains to
molecules and macrostructures...
-
Small interfering RNA (si
RNA),
sometimes known as
short interfering RNA or
silencing RNA, is a
class of double-stranded non-coding
RNA molecules, typically...
-
interfering RNA (si
RNA) and
micro RNA (mi
RNA) to
prevent m
RNA translation and/or
degrade m
RNA. However,
RNA aptamers are short,
single stranded RNA molecules...
- ALC-0159 is a
PEG/lipid
conjugate (i.e.
PEGylated lipid), specifically, it is the N,N-dimyristylamide of 2-hydroxyacetic acid, O-pegylated to a
PEG chain m****...
-
transfected cells may
translate the
RNA into the
encoded protein. If the
RNA is a
regulatory RNA (such as a mi
RNA), the
RNA may
cause other changes in the...
