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implicated in
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mutations in
genes p53, ATM, CEBPA, and
PPARgamma).
Marfan syndrome is
caused by
mutations in the FBN1 gene,
located on...
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- ↓Ca2+, ↑K+ ↓SMC
proliferation ↑Vasodilation
Antiproliferative ↑cAMP ↑
PPARgamma ↓Fibroblast
growth ↑Apoptosis
Antithrombotic ↓Thromboxane-A2 ↓PDGF ↓Platelet...