-
encoded by the
PDGFRB gene.
Mutations in
PDGFRB are
mainly ****ociated with the
clonal eosinophilia class of malignancies. The
PDGFRB gene is located...
-
mutations in
either the
PDGFRB or NOTCH3 gene. However, most IMF
cases have no
family history of the
disease but
nonetheless have
PDGFRB gene
mutations in their...
-
rearrangements in PDGFRA,
PDGFRB, or FGFR1. CEL not
otherwise specified (CEL NOS) is a form in
which BCR-ABL1
fusion genes and PDGFRA,
PDGFRB, and FGFR1 rearrangements...
- must be >1x109/L, no
Philadelphia chromosome or
mutations in the
PDGFRA or
PDGFRB gene
should be present, the
blast count must be <20% and
dysplasia of at...
-
lymphoid neoplasms ****ociated with
eosinophilia and
abnormalities of PDGFRA,
PDGFRB, FGFR1, and, tentatively, PCMA-JAK2. Informally,
these diseases are also...
- this condition:
PDGFB on
chromosome 22 and
PDGFRB on
chromosome 5.
These genes are
biochemically linked:
PDGFRB encodes the platelet-derived
growth factor...
-
Myeloid and
lymphoid neoplasms with
eosinophilia and
abnormalities of PDGFRA,
PDGFRB, or FGFR1 (i.e. high
eosinophil blood counts caused by
mutations in the...
- Myeloid/lymphoid
neoplasms with
PDGFRA rearrangement Myeloid/lymphoid
neoplasms with
PDGFRB rearrangement Myeloid/lymphoid
neoplasms with FGFR1
rearrangement Myeloid/lymphoid...
-
Kosaki overgrowth syndrome is a rare
syndrome caused by
mutations in the
PDGFRB gene. The
features of this
syndrome affect the face, skin,
brain and the...
- (2015). "Hematolymphoid
neoplasms ****ociated with
rearrangements of PDGFRA,
PDGFRB, and FGFR1".
American Journal of
Clinical Pathology. 144 (3): 377–92. doi:10...
