Definition of PDGFRA. Meaning of PDGFRA. Synonyms of PDGFRA

Here you will find one or more explanations in English for the word PDGFRA. Also in the bottom left of the page several parts of wikipedia pages related to the word PDGFRA and, of course, PDGFRA synonyms and on the right images related to the word PDGFRA.

Definition of PDGFRA

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Meaning of PDGFRA from wikipedia

- a wide range of cell types. The protein is encoded in the human by the PDGFRA gene. This receptor binds to certain isoforms of platelet-derived growth...
- as tumors whose behavior is driven by mutations in the KIT gene (85%), PDGFRA gene (10%), or BRAF kinase (rare). 95% of GISTs stain positively for KIT...
- harboring the platelet-derived growth factor receptor alpha (PDGFRA) exon 18 mutation, including PDGFRA D842V mutations. Avapritinib is also indicated for the...
- and lymphoid neoplasms ****ociated with eosinophilia and abnormalities of PDGFRA, PDGFRB, FGFR1, and, tentatively, PCMA-JAK2. Informally, these diseases...
- a study conducted in 2011 on various Asian po****tions, variants in the PDGFRA gene on chromosome 4q12 were identified to be ****ociated with corneal astigmatism...
- a) Myeloid and lymphoid neoplasms with eosinophilia and abnormalities of PDGFRA, PDGFRB, or FGFR1 (i.e. high eosinophil blood counts caused by mutations...
- is a diagnosis of exclusion, after clonal eosinophilia (such as FIP1L1-PDGFRA-fusion induced hypereosinophelia and leukemia) and reactive eosinophilia...
- proneural subtype often has high rates of alterations in TP53 (p53), and in PDGFRA the gene encoding a-type platelet-derived growth factor receptor. The mesenchymal...
- count must be >1x109/L, no Philadelphia chromosome or mutations in the PDGFRA or PDGFRB gene should be present, the blast count must be <20% and dysplasia...
- receptor alpha gene (PGDFRA) gene. The product of PDGFRA, platelet-derived growth factor receptor alpha (PDGFRA), is a tyrosine kinase receptor of the RTK class...