- as PDGF-C, is a 345-amino acid
protein that in
humans is
encoded by the
PDGFC gene. Platelet-derived
growth factors are
important in
connective tissue...
-
different receptors.
Known ligands include: PDGF-AA (PDGFA), -BB (PDGFB), -CC (
PDGFC), and -DD (PDGFD), and -AB (a
PDGFA and
PDGFB heterodimer). The ligands...
- Q9HBH1 11883
PDGFA HGNC:8799 P04085 11884
PDGFB HGNC:8800 P01127 11885
PDGFC HGNC:8801 Q9NRA1 11886
PDGFD HGNC:30620 Q9GZP0 11887
PDGFRA HGNC:8803 P16234...
- location, exon structure, and
vascular expression patterns of the
human PDGFC and
PDGFC genes". Circulation. 103 (18): 2242–7. doi:10.1161/01.cir.103.18.2242...
-
lacking functional genes for both
these PDGFRA activating ligands, i.e. Pdgfa/
Pdgfc-
double null mice show
similar defects to
Pdgra null mice. Mice genetically...
- MASP2, MFRP, NETO1, NETO2, NRP1, NRP2, OVCH1, OVCH2, PCOLCE, PCOLCE2,
PDGFC, PDGFD, PRSS7, RAMP, SCUBE1, SCUBE2, SCUBE3, SEZ6, SEZ6L, SEZ6L2, ST14,...
- FOXE1, IRF6, MAFB (gene), MMP3, MSX1, MSX2 (Msh
homeobox 2), MSX3, PAX7,
PDGFC, PTCH1, SATB2, SOX9, SUMO1 (Small ubiquitin-related
modifier 1), TBX22,...
- H1703,
which is
reported to have
amplification of both
PDGFRA (4q12) and
PDGFC (4q32)
genes on
chromosome 4, and also
overexpress PDGFRα, was sensitive...
