- An
oxysterol is a
derivative of
cholesterol obtained by
oxidation involving enzymes and / or pro-oxidants. Such
compounds play
important roles in various...
- The
oxysterol-binding
protein (OSBP)-related
proteins (ORPs) are a
family of
lipid transfer proteins (LTPs). Concretely, they
constitute a
family of sterol...
- CYP39A1
oxysterol 7alpha-hydroxylase.
Steroidogenic enzyme Li-Hawkins J, Lund EG,
Bronson AD,
Russell DW (2000). "Expression
cloning of an
oxysterol 7alpha-hydroxylase...
-
interest in
oxysterols arose when they were
shown to
exert inhibitory actions on
cholesterol biosynthesis. This
finding became known as the "
oxysterol hypothesis"...
- 14.13.100, 25-hydroxycholesterol 7alpha-monooxygenase, CYP7B1, CYP7B1
oxysterol 7alpha-hydroxylase) is an
enzyme with
systematic name cholest-5-ene-3beta...
-
Oxysterol-binding
protein 1 is a
protein that in
humans is
encoded by the OSBP gene.
Oxysterol-binding
protein (OSBP) is an
intracellular protein that...
- EBI2 is a
receptor for
oxysterols. The most
potent activator is 7α,25-dihydroxycholesterol (7α,25-OHC), with
other oxysterols exhibiting varying affinities...
-
classified as
orphan nuclear receptors, however, upon
discovery of
endogenous oxysterols as
ligands they were
subsequently deorphanized. Two
isoforms of LXR have...
- However, Fred
Kummerow claims that it is not
dietary cholesterol, but
oxysterols, or
oxidized cholesterols, from
fried foods and smoking, that are the...
- hormone-binding
protein Vitamin D-binding
protein Syntaxin binding protein 2
Oxysterol-binding
protein E3
binding protein Iron-responsive element-binding protein...