- The
oxoeicosanoids are
nonclassic eicosanoids,
derived from
arachidonic acid (AA). For example,
Lipoxygenase produces 5-HETE from AA; a
dehydrogenase then...
-
Oxoeicosanoid receptor 1 (OXER1) also
known as G-protein
coupled receptor 170 (GPR170) is a
protein that in
humans is
encoded by the OXER1 gene located...
- or 'nonclassic eicosanoids'.
These included the
following classes:
Oxoeicosanoids (oxo-ETE)
include the
following metabolites: 5-Oxo-eicosatetraenoic...
- in
human eosinophils, neutrophils, and
monocytes by
binding to the
Oxoeicosanoid receptor 1,
which like the
receptors for
leukotriene B4, is a G protein-coupled...
-
hydroxyeicosatetraenoic acids (HETEs), e.g. 5-HETE and 12-HETE; and
oxoeicosanoids (oxo-ETE), e.g. 5-oxo-eicosatetraenoic acid (5-oxo-ETE) and 12-oxo-ETE...
- by GPR99/OXGR1, may
constitute a
third CysLTR.
Eicosanoid receptor Oxoeicosanoid receptor Prostaglandin receptor Thromboxane receptor Kanaoka Y, Maekawa...
-
Yokomizo T,
Rovati GE (2014). "Update on leukotriene,
lipoxin and
oxoeicosanoid receptors:
IUPHAR Review 7".
British Journal of Pharmacology. 171 (15):...
- 5-HETE, 12-HETE), the
hydroxylated heptadecatrienoic acid, 12-HHT, and
oxoeicosanoids (e.g. 5-oxo-ETE).
These agents functioned as pro-inflammatory signals...
-
various other neutrophil stimuli. This 5(S)-HETE
receptor is
termed the
oxoeicosanoid receptor 1 (abbreviated as OXER1). 5(S)-HETE is a
product of the cellular...
-
through it to
stimulate pro-inflammatory
responses in
target cells Oxoeicosanoid:
Oxoeicosanoid (OXE)
receptor 1 – OXER1; OXER1 is the
receptor for 5-oxo-eicosatetraenoic...
