-
compound containing both
nitrogen and
oxygen in a 5-membered ring.
Oxazolidinones are a
class of
compounds containing 2-oxazolidone in the structure....
-
resistance to
linezolid has
remained low.
Linezolid is a
member of the
oxazolidinone class of medications.
Linezolid was
discovered in the mid-1990s, and...
-
through Zimmermann-Traxler methods, and then the
oxazolidinone cleaved away.
Commercial oxazolidinones are
relatively expensive, but
derive in 2 synthetic...
-
synthesis of the
macrolide cytovaricin,
considered a classic,
utilizes oxazolidinone chiral auxiliaries for one
asymmetric alkylation reaction and four asymmetric...
-
Clindamycin Ethambutol Lincosamides Macrolides Nitrofurantoin Novobiocin Oxazolidinone Spectinomycin Sulfonamides Tetracyclines Tigecycline Trimethoprim List...
-
development of
aldol reaction methodology (for example, Evans' acyl
oxazolidinone method).
Evans was born on
January 11, 1941, in Washington, D.C. He...
- Tedizolid, sold
under the
brand name
Sivextro (by Merck) is an
oxazolidinone-class antibiotic.
Tedizolid phosphate is a
phosphate ester prodrug of the...
- to
conclude that the
involvement of
oxazolidinone is only parasitic.
Blackmond in 2004 also
found oxazolidinones as
intermediates (NMR) in a
related proline-catalysed...
-
David A. (1990). "Diastereoselective
Aldol Condensation Using a
Chiral Oxazolidinone Auxiliary: (2S,3S)-3-Hydroxy-3-phenyl-2-methylpropanoic Acid". Org....
-
bacterial 50S
ribosome subunit,
overlapping with the
binding sites of the
oxazolidinone, pleuromutilin, and
macrolide antibiotics,
among others. The binding...
